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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b778de80177ac19ecca5850e5df03e40c951cdeb83137353f89fbcaa58b32d6f' 
  AND token = 'aZGWkoprz7psR4HWE0ONRpH3oT0utSHHy138WZFWhEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}