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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f636b57937c081f03f437fc11b624828b8e0a50af9793df2c3379daf41ba279' 
  AND token = 'ewy3wf/eYP3Pc239e0S4PKAg9aSfD+Yy9ABddZwrglA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}