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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e1d1d14f8efa296b6a22624ddbf94d36dbae74591ad0faedf2285f30213a55' 
  AND token = 'vYmac1R+wpaEd6O1SAgCQwEQOBlCvst6+6xjCBrfzEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}