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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9785deb0eccc82d78e273f96298aebc326ca0b989e6f1032001b39beb1be95a' 
  AND token = 'qA4psw0tFYpMx5WBR+B7AQ0hCRDWDylak7bcYbl8h0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}