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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4836805b3bd7c774900d4434fdb87da3ad48a5d27bb77daeb91ac976e4ba43f6' 
  AND token = 'cbIcb1zkEcCb1IDupMiTYvoiZDgUq1oBcLfr4oKWa4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}