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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645ec3b0adcfcaabfde59ef867407258b8cf7b1c9d84f4a418e652a74e0e72be' 
  AND token = 'zYOG9rp3Tm9KonPIit4sVF5UCIzSRI2KjuXXQ95MGy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}