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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6397963f301bc3208ddad27b28e87a7d1f5ef8d626f4f3c1eb9a116b43323b3b' 
  AND token = '9QtTas713C5qadHEn33q++MxcZNkXu29kdcuRUhkaso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}