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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '176a106fb7aff5c00e1705662385f64a2b02eca724cd1df2b318ada984e4c0b4' 
  AND token = '+UeOD8SQiOFBwk9kcxcRwgR8SjFkKWbCbtmCR9nFGB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}