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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1f629ce3b8ebd89a972795a31bcedbc50be65cce56e4a9f24f8ec6b08971f19' 
  AND token = 'IlupNJ7XLlxmAtQvarmQuFPLU/EKJEToJKiuPgRBdog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}