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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c0c4ad3eab4cd735c4ae3396dd8326734b4def615dcdd467de88fc117996b8c' 
  AND token = 'o8g6XvYFdHexXiqkh+9ta1OrAYqqAD9Zifx51Z+sLQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}