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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb04129de4e8e61ac647d3cd021f1686e79fa2c8f21bfb0c8ad17a7c2589845' 
  AND token = 'Ca+h36Jt4mzbROCvdCdoK9njuOkQc/qPWKwh4eor61o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}