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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a4ffc14396583f9bb5688e5752a0f5894c5f7a9a9e1ab27dba7e996cb2b48e5' 
  AND token = 'ZGHQC0Y+R82zCQeWgtKyp/z7AEjQeN7E841KA7UMrSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}