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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74073cde719551267a3bd458dcaf8ef0a8c1c3c50e5478c3d748bdfdd0bd8015' 
  AND token = '4UrL+R9B6PmLLFDjSXpmVXN1NBzQT3pb6/BUqV9bWZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}