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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbce924a53e863af5a0900b87679a50d0bd127f61671a5a9ed129430a0f6fc9b' 
  AND token = 'Vyq9bK7m+pHBUpo++1vCMdFfvm+ORt5xURctxDEXL7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}