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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61d0eabb8e41b465090625881f6ae2f0a9aa5841bc250b1cd849376ee31ce6f' 
  AND token = 'v//ZaOh3dftnl5NRej1j+ICl1nS+P9/Mp+0dAmrbuTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}