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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a432173db65c764b54e8f32e5fc3a3c28a37fcf6c478f1de648f15440a142334' 
  AND token = 'G7oD27mKCZExil/gkFeFzmWXjMjjxbgiolBdojMSwg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}