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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c066803fe0988d790434a9af30579b70de2d1b1cd4ddf1e5a3d65d80c97dae9' 
  AND token = 'G2+9jCK37unHvQicA8Qict7zZJaNttp81RecDDfhSoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}