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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1ee1536df7d8c6a884dea82af0844edd5815e9927c2b9bbbeaa0d2582348f8' 
  AND token = 'Lcsjc/0PoAgsK/TjF1kW/Tbn3CqprvH0s8mU3ChBBnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}