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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0145fa39d323b0c452a0564d49ed19c6878648ba9078409951f54a83d18fb23' 
  AND token = 'S04CBFr43lQeOxzGxyYtzqSsx/wz7DCmbCdTUjSDsxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}