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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fd29827560c9ff419017c1d3cf29a071e1c3e74e6ea3cb911eae1e4aa0309a2' 
  AND token = '8bl8CeAr3n2qdjKBUBODO0mqoD12QaSYrRuIFSgh4Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}