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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1cb6a8df1211e2db343f9762de54c3b2ce9d666108a025e98bb185740b873df' 
  AND token = 'H7Cw0uDF/Yc7dvUvufnLadc2zjFjAeHva4kDLlAS86Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}