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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '628e37d39f7899662a5c02592b6c08eaf1eb3a6ab7524cc974e54b9a3d70d2c1' 
  AND token = 'I5FyTQ99AkMdY4Y3ZQApAWYWUH5U70IJ4wIj3eKCxL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}