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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc5d0102edc5f55ff6d338cd8dcfd1e64497dc0eb4fbfece394689617d62c89a' 
  AND token = 'LTLxIR/EFO9mPYSYEFfVrd1wiOo5btxmaQz668RNbOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}