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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47075c5d282a41f07720182c2b1e72a318de65a2ef0d71fc7eb384c55ef5a561' 
  AND token = 'dRB+tgQja2Etj3XHTSCp3v8OUMoYdE9/mJjbqnVj7qA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}