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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b04f9e565590cae922e2eb1a25e9f8b4251aefd374d6b3ad255a59f7b5132c7' 
  AND token = 'XpaY47/4AjSJvrmj7hidLJL7nkdC2TBRwcWHl2n32zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}