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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f6c47702774ea52150a726cd36bbde9e5f74d1209de82a5d6654a7287b10668' 
  AND token = 'DEnU5ZA4dzy7ADL52Ysgzgbd6Hr/E0pwfBfJEAXlygs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}