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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '835b19646c27a54b878ceff9f6e0be1626c4b28d439c90cc571504d686509d49' 
  AND token = 'pjFL8w4mgO1qhrC8/bqNhZVxsOUeuLRNEtcrPd21d4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}