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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3c8fe98a1872cf6e5740a1f6961818f1454e01e1e91e461766d1f1c021d8f97' 
  AND token = 'S8xFTnwbZnTGJGVZzy2CCQwBuGeqnev05ndsqACKnrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}