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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c73c22b798ce95e1d46ff5a2a62c1698f30bf68202cf784cf5cdfdea443b1f' 
  AND token = 'rzcERx4WFEmd+fY4w6tD+EImGuKhRPpGXyHHsy9MRew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}