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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c722c173c80461b1e77453ea54fbd24e8e8a29bcfc228d153e8c69f248bf762' 
  AND token = 'Hq2v5Jh69UaS4R4Q1hZW/74QrcCzBH0bFOolOfdEJZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}