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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d435e7f248e5fa5e3f92ba35ffba66d9867834015ad0d17281c128a65d2950' 
  AND token = 'kFRJQPB2vD0ME5fqoQ2JkeBhs5zEaI0zFHcHHY1tHKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}