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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bf157d3d624c4ac7e6d8150fe66014b2575902397053838777d2778746b1e58' 
  AND token = 'DtBQLdoP9KJKwH3nIWf/Fc6FTMmxT2BtAt7fVxHRfR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}