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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef6b36cbc2c2bd5b6e8747887b5ddfc7c711e5c515eb031ded620f80acd21a4' 
  AND token = 'z3v6mx1xLUq+BNHfcysZ6zPKzXDk1jDHdqi1jrP4KsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}