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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80aab630b48c51de71539b1587f8f4e198c376d435f56fcfadc7266398f8370f' 
  AND token = '+7ReLUFs3MHaA024+o06ZtdvMjBzMtwm5DB3QqK0RVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}