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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f895f9767c67c6a49d162a90688931900c1c921f3107bd7875f5cc22cb38889' 
  AND token = 'N+a9Y3GTkp08kiPHivBqS00/5ArDRBkYZLsmyrAVlMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}