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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14986cdbb0267379f8035e487a60920e1eb7574d7e301ddbd18fe70d9fd670d6' 
  AND token = 'wLtJ+MURmkLTEC7OZPYBETWOqnnTnPAsnzxHDfXXKJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}