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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b02b5e929969b88cf42e4239c4cf81d9570da1b68f5c7d9750ac40fa54a266' 
  AND token = 'xqZAwiNsZoFVTPeZNg7/oyr7vXP2Yu7iMfoXvX0G1sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}