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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35176101f2bc19b72949eb1978a3f97f38352865c9120344d537793fa87fea22' 
  AND token = 'gi7xkxC0j7wpBVIT+5QcrpYa7ZWnCQ+7+hMer98oJQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}