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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c892f4f57cc219c45c1910bba267826edf583c4c7c17ec93be253d1ba0edac' 
  AND token = 'F1TRUQW8v/ixpeDf8v4Y+Y9X0sjaCwJdiYwSGJwXETg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}