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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec82b68bd029addf652268b098f7290b7b8766e1b5963c40f09daeb751d46468' 
  AND token = 'JZ9IX6Zl5THpvNcIBj8uSKd4WTuL/t7NJ270qbQX++w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}