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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287fa6aa141b812400d55ca470cc9c542e80317d5e2f8d2798e7525239494cfb' 
  AND token = 'Fmh+3sftACOe16B5+Sx6bzKzxXf3dWoMubuV+9qi7ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}