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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f509d76f6a8f1420304f299bea8ceff8014d5c492408bde2a2c09fc3ca1f75c' 
  AND token = 'Sibv67LY+2PaiQhAdm/IHS8MN1ksnoIKxdz21bvCWcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}