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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f81a64d17777bda7656657df55a0fdb1b66d175965fb707785de3f77c50154d' 
  AND token = 'wWJ/PD/1t3z5z/fQbjFBq4o1S6k3fODWsb5WwPjfQJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}