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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d86ef4fb655a5c9f21571027cbf8506b0634e9a70d44c274713b154cee431d1' 
  AND token = 'ROY0VtA+BviP/at4MGFoY/8SdG8lsq6VibRLM2ryjPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}