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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c80710b3454b73afd2fb769bd7c120c699d3dfcb25292edca6e6bb1cffc878' 
  AND token = 'Rem/JukTKgOGQzvUlq7iO3AeD9QHsF0oNPNvWTOhNTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}