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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7c799648ca929bd351c8849d7842c3c7f792a7bf62e4ba40c35adb755db6e7' 
  AND token = 'YOIpNXSsqlLija6oc1UlkvUfr4Y7poLn+g9nisG1mNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}