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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ee0302339cd772d13cf069b10af0553a4ec79f3144c86a01c7eaa3255b28187' 
  AND token = '1yYKQXAEQ4UUxSwdcDMOciYDwR5hefj71cvOUSSLncU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}