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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cd404da669bc76f76dbc039f465a24fe125c577d674f7360e1ac1032d0db5cc' 
  AND token = 'O/Undm/AM+UlSwx0Xsa3CFQ2YPfLzZxGP7eCRYvDI3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}