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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '196c74fc0165f8690cee2681a34abc9486a9cdb9999fc90b1b9951be232232c4' 
  AND token = '2C2ACn3a/+O0UCrP/9jqcFD+nx0mYZQh6Dhx2hxqVFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}