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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '629645667b71d91ca092d333f2ad6d8ca893fa95dd46c51807899648a0fb14ca' 
  AND token = 'HjMOe5Lae8UBZWTm+WIgNJe/6LaZOmlFrET7X7SuQUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}